originally published February 2018 – updated July 2025

If your results have plateaued with traditional supplements, it might be time to explore the next level, and 1-Andro could be the performance enhancer you’re looking for.

Short for 1-androstene-3b-ol, 17-one, 1-Andro is a non-methylated prohormone that converts to 1-testosterone, a potent compound known for supporting lean muscle gains, strength, and improved body composition. 

Unlike other prohormones, it doesn’t convert to estrogen or DHT, which means fewer side effects — and more results.

Despite its potency, 1-Andro is currently not classified as a controlled substance under the 2014 Designer Anabolic Steroid Act and remains available for legal sale in the U.S. 

Keep reading for a complete breakdown of its benefits, results, and what you need to know before starting a cycle.

What to Expect with 1-Andro and How It Works

1-Andro delivers many of the benefits users associate with classic prohormones — but with fewer side effects thanks to its unique structure.

What to Expect from a 1-Andro Cycle

Users commonly report the following when taking 1-Andro supplements:

• Increased strength and size
• Noticeable lean muscle gains
• Faster post-workout recovery
• Improved body composition

Some individuals have reported gaining up to 10 lbs of lean muscle and reducing body fat by as much as 5% during a properly supported cycle. While results vary, these gains are possible when paired with a dialed-in training and nutrition plan.

Because 1-Andro is non-methylated and doesn’t convert to estrogen or DHT, it avoids many of the harsher side effects associated with banned designer anabolics.

How 1-Andro Works in the Body

Once ingested, 1-Andro converts into 1-testosterone, a potent anabolic compound. Unlike other compounds that can lead to water retention or estrogen-related side effects, 1-testosterone does not aromatize, meaning:

• No estrogen conversion
• No need for anti-estrogens
• Lower risk of estrogen-related side effects

Bottom line: 1-Andro offers a clean, efficient pathway to strength and muscle growth without the hormonal backlash of older prohormones.

Potential Side Effects of 1-Andro

While 1-Andro is known for having minimal side effects compared to many other prohormones, it’s still important to be aware of how your body may respond. 

Most users tolerate it well, especially when using proper cycle support, but some may experience:

• Back Pumps: This sensation feels like a cramping in the lower back, often triggered during heavy lifts. Supplementing with taurine can help reduce discomfort.
• Elevated Blood Pressure: Like other prohormones, 1-Andro may cause temporary increases in blood pressure. Monitor your levels regularly. If you experience severe symptoms, such as persistent headaches, consult your physician.
• Decreased Libido: Although 1-Andro converts into 1-testosterone, some users report a temporary drop in libido during their cycle. This drop usually resolves post-cycle and can often be mitigated with proper support supplements.
• Hair Shedding: Though 1-Andro doesn’t convert to DHT (a hormone linked to male-pattern baldness), some users may notice increased hair shedding. This effect typically subsides once the cycle ends.

Stacking 1-Andro: What You Need to Know

One of the most significant advantages of 1-Andro is its stacking flexibility. It pairs well with foundational supplements like creatine and BCAAs. However, for best results and safety, certain products are non-negotiable.

Essential Stack Components

To support your body during a cycle and protect long-term health, you should always include:

• Cycle Support: Helps maintain blood pressure, liver function, and hormone balance throughout the cycle.
• Post Cycle Therapy (PCT): Assists in natural testosterone recovery and prevents unwanted hormonal side effects after your cycle ends.

Don’t skip out on your supporting supplements; a proper stack keeps your results clean and your body functioning at its best.

Stacking with Other Prohormones

Some 1-Andro products come pre-stacked with additional non-banned prohormones for enhanced results. These often include:

• 4-Andro for added mass and strength
• Epi-Andro for muscle hardness and increased aggression in the gym

Whether you’re building your own stack or choosing a blended formula, make sure to research the compounds and align them with your fitness goals.

Cycling 1-Andro Safely

When using any prohormone, including 1-Andro, following the manufacturer’s dosing instructions is the safest and most effective approach. 

Each product may vary slightly in its formulation, so it is essential to start with the guidance on the label.

Typical Cycle Length and Dosage

Cycle duration: Most 1-Andro cycles last between 4 and 8 weeks, depending on your training experience and goals.

Dosage range: Recommendations across sources can vary widely, from as low as 200 mg per day to upwards of 1000 mg per day. 

If you’re considering a higher dose, be sure to factor in your body weight, cycle history, and overall health.

A Note on Safety

Keep in mind that 1-Andro is a hormonal supplement. Taking more than advised can increase the risk of side effects and place unnecessary strain on your body. 

Stick with trusted sources, listen to your body, and always include proper cycle support and PCT to protect your health.

For new users, it’s best to start on the lower end of the dosage spectrum and evaluate how your body responds before increasing the dose.

Final Thoughts on Adding 1-Andro to Your Prohormone Stack

1-Andro is a powerful option for athletes ready to move beyond the basics and push for serious results. With proper cycle support, PCT, and a responsible approach, it offers lean muscle gains and strength improvements with minimal side effects.

Whether you’re stacking or running it solo, 1-Andro can help take your training to the next level, as long as you’re informed and intentional.

Ready to build your next prohormone stack? Explore our selection of prohormones at Black Diamond Supplements and get expert support from our team any time you need it.